we have a 3-year postdoc position available within our Wellcome Investigator Award. We are looking for a postdoc with experience in bacterial infection models, ideally both in vitro and in mouse models. Would be great if you would like to learn a little about proteomics along the way.

this project will utilise a novel, sensitive proteomics approach to characterise bacterial phagosomes.

apply here: https://jobs.ncl.ac.uk/job/Newcastle-Research-AssistantAssociate-Proteomics-characterization-of-bacterial-phagosomes/833892001/

Congratulations to Leonie and Ruth who won the Poster prizes at the MosMed conference and the BSPR 2022 annual meeting, respectively!

Well done!

The advert for our fully funded MosmedC studentship in Collaboration with Sarah Rice and Startup Nuchido is now live on FindAPhD https://www.findaphd.com/phds/project/linking-epigenomics-with-cellular-senescence-to-identify-novel-therapeutics-for-osteoarthritis/?p142037

Email for more details.

Delia and Sara are joining our lab as international BSc students to do their final year project with Jose in the lab. They will work on a specific E3 ligase that appears to have relevance in viral infections.

Welcome!

A warm welcome to Imogen and Oenone who joined the lab to do their undergraduate projects with Ben and Joe, respectively.

Finally out! A great paper by amazing postdocs Olivier and Anetta.

Govaere, O., Martinez-Lopez, N., Kragh Petersen, S., Mancina, R.M., Bel Lassen, P., Darlay, R., Peltier, J., Younes, R., Tiniakos, D., Aithal, G.P., Allison, M., Vacca, M., Yki-Järvinen, H., Dufour, J.-F., Ekstedt, M., Francque, S., Petta, S., Bugianesi, E., Schattenberg, J.M, Day, C.P., Cordell, H.J, Clément, K., Romeo, S., Ratziu, V., Daly, A.K., Anstee, Q.M*, Trost, M.*, Härtlova, A.*, Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in human obesity-related non-alcoholic fatty liver disease, (2021), Journal of Hepatology, Dec 20:S0168-8278(21)02254-6. Link

A nice collaboration with Chris Duncan’s lab on “Delayed induction of type I and III interferons and nasal epithelial cell permissiveness to SARS-CoV-2” has just been published in Nature Communications.

Congratulations to all involved, particularly, Maria who led this work from our lab!

Hatton, C.F*, Botting, R.A.*, Dueñas, M.E.*, Haq, I.J., Verdon, B., Thompson, B.J., Stremenova Spegarova, J., Gothe, F., Stephenson, E., Gardner, A.I., Murphy, S., Scott, J., Garnett, J.P., Carrie, S., Hussain, R., Coxhead, J., Davey, T., Simpson, A.J., Haniffa, M., Hambleton, S., Brodlie, M., Ward, C., Trost, M., Reynolds, G., Duncan, C.J.A, Delayed induction of type I and III interferons and nasal epithelial cell permissiveness to SARS-CoV-2, (2021) Nature Communications Dec 7;12(1):7092. (*co-first authors)

A warm welcome to Andrew Frey who has joined us to work with us on the role of ubiquitylation on the phagosome!