Matthias Trost on Google Scholar

Heap, R.E., Hope, A., Pearson, L.A., Reyskens, K.M.S.E., MacGowan, S., Hastie, J., Porter, D., Arthur, J.S.C, Gray, D.W. and Trost, M., Identifying inhibitors of Inflammation: A novel high-throughput MALDI-TOF screening assay for salt inducible kinases (SIKs), SLAS Discovery (2017)

Selvan, N., Williamson, R., Mariappa, D., Campbell, D.G., Gourlay, R., Ferenbach, A.T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. and van Aalten, D.M.F., Native enrichment of the Drosophila O-GlcNAc proteome reveals candidate conveyors of the supersex combs phenotype, Nature Chem Biol (2017), Jun 12.

Pauwels, A.-M., Trost, M., Beyaert, R. and Hoffmann, E., Patterns, Receptors and Signals: Regulation of Phagosome Maturation, Trends in Immunology (2017), Jun;38(6):407-422

Magiera, K., Tomala, M., Kubica, K., De Cesare, V., Trost, M., Zieba, B.J., Kachamakova-Trojanowska, N., Les, M., Dubin, G., Holak, T.A. and Skalniak, L. Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a, Cell Chem Biol (2017), Apr 20;24(4):458-470.

Hartlova, A., Peltier, J., Bilkei-Gorzo, O. and Trost, M. (2017). Isolation and Western Blotting of Latex-Bead Phagosomes to Track Phagosome Maturation. Methods Mol Biol 1519, pp. 241-248

Peltier, J., Hartlova, A. and Trost, M. (2017). Assessing the Phagosome Proteome by Quantitative Mass Spectrometry. Methods Mol Biol 1519, pp. 249-263

Cianfanelli, F. R., Alcoforado Diniz, J., Guo, M., De Cesare, V., Trost, M. and Coulthurst, S. J.(2016). VgrG and PAAR Proteins Define Distinct Versions of a Functional Type VI Secretion System. PLoS Pathog 12, pp. e1005735

Gandin, V., Masvidal, L., Cargnello, M., Gyenis, L., McLaughlan, S., Cai, Y., Tenkerian, C., Morita, M., Balanathan, P., Jean-Jean, O., Stambolic, V., Trost, M., Furic, L., Larose, L., Koromilas, A. E., Asano, K., Litchfield, D., Larsson, O. and Topisirovic, I. (2016). mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun 7, pp. 11127

Hjerpe, R., Bett, J. S., Keuss, M. J., Solovyova, A., McWilliams, T. G., Johnson, C., Sahu, I., Varghese, J., Wood, N., Wightman, M., Osborne, G., Bates, G. P., Glickman, M. H., Trost, M., Knebel, A., Marchesi, F. and Kurz, T. (2016). UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome. Cell 166, pp. 935-49

Huguenin-Dezot, N., De Cesare, V., Peltier, J., Knebel, A., Kristaryianto, Y. A., Rogerson, D. T., Kulathu, Y., Trost, M. and Chin, J. W. (2016). Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity. Cell Rep 16, pp. 1180-1193

McGuire, V. A., Ruiz-Zorrilla Diez, T., Emmerich, C. H., Strickson, S., Ritorto, M. S., Sutavani, R. V., Weibeta, A., Houslay, K. F., Knebel, A., Meakin, P. J., Phair, I. R., Ashford, M. L., Trost, M. and Arthur, J. S. (2016). Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation. Sci Rep 6, pp. 31159

Naujoks, J., Tabeling, C., Dill, B. D., Hoffmann, C., Brown, A. S., Kunze, M., Kempa, S., Peter, A., Mollenkopf, H. J., Dorhoi, A., Kershaw, O., Gruber, A. D., Sander, L. E., Witzenrath, M., Herold, S., Nerlich, A., Hocke, A. C., van Driel, I., Suttorp, N., Bedoui, S., Hilbi, H., Trost, M. and Opitz, B. (2016). IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid. PLoS Pathog 12, pp. e1005408

Steger, M., Tonelli, F., Ito, G., Davies, P., Trost, M., Vetter, M., Wachter, S., Lorentzen, E., Duddy, G., Wilson, S., Baptista, M. A., Fiske, B. K., Fell, M. J., Morrow, J. A., Reith, A. D., Alessi, D. R. and Mann, M. (2016). Phosphoproteomics reveals that Parkinson’s disease kinase LRRK2 regulates a subset of Rab GTPases. Elife 5, pp. e12813

Bett, J. S., Ritorto, M. S., Ewan, R., Jaffray, E. G., Virdee, S., Chin, J. W., Knebel, A., Kurz, T., Trost, M., Tatham, M. H. and Hay, R. T. (2015). Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers. Biochem J 466, pp. 489-498

Dill, B. D., Gierlinski, M., Hartlova, A., Arandilla, A. G., Guo, M., Clarke, R. G. and Trost, M.(2015). Quantitative proteome analysis of temporally resolved phagosomes following uptake via key phagocytic receptors. Mol Cell Proteomics 14, pp. 1334-1349

Guo, M., Hartlova, A., Dill, B. D., Prescott, A. R., Gierlinski, M. and Trost, M. (2015). High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow derived macrophages. Proteomics 15, pp. 3169-3174

Kazlauskaite, A., Martinez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. and Muqit, M. M. (2015). Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation. EMBO Rep 16, pp. 939-954

Lai, Y. C., Kondapalli, C., Lehneck, R., Procter, J. B., Dill, B. D., Woodroof, H. I., Gourlay, R., Peggie, M., Macartney, T. J., Corti, O., Corvol, J. C., Campbell, D. G., Itzen, A., Trost, M. and Muqit, M. M. (2015). Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1. EMBO J 34, pp. 2840-61

Gawden-Bone, C., West, M. A., Morrison, V. L., Edgar, A. J., McMillan, S. J., Dill, B. D., Trost, M., Prescott, A., Fagerholm, S. C. and Watts, C. (2014). A crucial role for beta2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells. J Cell Sci 127, pp. 4213-4224

Hamilton, J. J., Marlow, V. L., Owen, R. A., Costa Mde, A., Guo, M., Buchanan, G., Chandra, G., Trost, M., Coulthurst, S. J., Palmer, T., Stanley-Wall, N. R. and Sargent, F. (2014). A holin and an endopeptidase are essential for chitinolytic protein secretion in Serratia marcescens. J Cell Biol 207, pp. 615-626

Kazlauskaite, A., Kondapalli, C., Gourlay, R., Campbell, D. G., Ritorto, M. S., Hofmann, K., Alessi, D. R., Knebel, A., Trost, M. and Muqit, M. M. (2014). Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65. Biochem J 460, pp. 127-139

Navarro, M. N., Feijoo-Carnero, C., Arandilla, A. G., Trost, M. and Cantrell, D. A. (2014). Protein kinase D2 is a digital amplifier of T cell receptor-stimulated diacylglycerol signaling in naive CD8+ T cells. Sci Signal 7, pp. ra99

Ritorto, M. S., Ewan, R., Perez-Oliva, A. B., Knebel, A., Buhrlage, S. J., Wightman, M., Kelly, S. M., Wood, N. T., Virdee, S., Gray, N. S., Morrice, N. A., Alessi, D. R. and Trost, M. (2014). Screening of DUB activity and specificity by MALDI-TOF mass spectrometry. Nat Commun 5, pp. 4763

Tape, C. J., Worboys, J. D., Sinclair, J., Gourlay, R., Vogt, J., McMahon, K. M., Trost, M., Lauffenburger, D. A., Lamont, D. J. and Jorgensen, C. (2014). Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC. Anal Chem 86, pp. 10296-10302

Edgar, A. J., Trost, M., Watts, C. and Zaru, R. (2013). A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870. Biosci Rep

Fritsch, M. J., Trunk, K., Diniz, J. A., Guo, M., Trost, M. and Coulthurst, S. J. (2013). Proteomic identification of novel secreted antibacterial toxins of the Serratia marcescens type VI secretion system. Mol Cell Proteomics 12, pp. 2735-2749

Ritorto, M. S., Cook, K., Tyagi, K., Pedrioli, P. G. and Trost, M. (2013). Hydrophilic Strong Anion Exchange (hSAX) Chromatography for Highly Orthogonal Peptide Separation of Complex Proteomes. J Proteome Res 12, pp. 2449-2457

Ritorto, M. S., Trost, M. and Cook, K. (2013). Hydrophilic strong anion exchange chromatography for proteomics: what’s the future outlook?. Bioanalysis 5, pp. 2219-2221

Trost, M., Sauvageau, M., Herault, O., Deleris, P., Pomies, C., Chagraoui, J., Mayotte, N., Meloche, S., Sauvageau, G. and Thibault, P. (2012). Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia. Blood 120, pp. e17-27

Campbell-Valois, F. X., Trost, M., Chemali, M., Dill, B. D., Laplante, A., Duclos, S., Sadeghi, S., Rondeau, C., Morrow, I. C., Bell, C., Gagnon, E., Hatsuzawa, K., Thibault, P. and Desjardins, M.(2012). Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome. Mol Cell Proteomics 11, pp. M111 016378

Deleris, P., Trost, M., Topisirovic, I., Tanguay, P. L., Borden, K. L., Thibault, P. and Meloche, S.(2011). Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway. J Biol Chem 286, pp. 6470-6478

Boulais, J., Trost, M., Landry, C. R., Dieckmann, R., Levy, E. D., Soldati, T., Michnick, S. W., Thibault, P. and Desjardins, M. (2010). Molecular characterization of the evolution of phagosomes. Mol Syst Biol 6, pp. 423

Trost, M., Bridon, G., Desjardins, M. and Thibault, P. (2010). Subcellular phosphoproteomics. Mass Spectrom Rev 29, pp. 962-90

Trunk, K., Benkert, B., Quack, N., Munch, R., Scheer, M., Garbe, J., Jansch, L., Trost, M., Wehland, J., Buer, J., Jahn, M., Schobert, M. and Jahn, D. (2010). Anaerobic adaptation in Pseudomonas aeruginosa: definition of the Anr and Dnr regulons. Environ Microbiol 12, pp. 1719- 33