Maria led the writing of this wonderful review in EMBO Mol Medicine together with colleagues from GSK (including our own ex-student Rachel Heap) and BI.

Read it here:

https://www.embopress.org/doi/full/10.15252/emmm.202114850

A new amazing paper on how lysosomal damage through Mtb drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

Tiaan did the cool mass spec for this!

https://www.nature.com/articles/s41467-022-34632-8

…and Maria’s first last-author paper!

A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1

https://slas-discovery.org/article/S2472-5552(22)13707-X/fulltext

https://portlandpress.com/biochemist/article/44/5/2/232007/MALDI-TOF-mass-spectrometry-in-the-21st-century

Characterising the role of ubiquitylation in endo-lysosomal trafficking by highly sensitive ion mobility mass spectrometry

We are looking for a talented PhD student to join us in September 2023. Exciting novel technology, exciting, impactful biology. Apply online and send an email to Matthias to discuss.

https://www.findaphd.com/phds/project/characterising-the-role-of-ubiquitylation-in-endo-lysosomal-trafficking-by-highly-sensitive-ion-mobility-mass-spectrometry/?p150331

Congratulations to Jack and Jose for publishing this great review on the role of macrophage scavenger receptor 1 (MSR1) in inflammatory disorders and cancer.

See the open access article here: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1012002/full

Congratulations to Orsi, Jose, Anetta and all the others involved in this great paper on the role of ubiquitylation on the phagosome!

see the paper here:

https://doi.org/10.15252/embj.2021108970

we will host the BSPR and EUPA 2023 in Newcastle!

Atakan made a great website which will be populated in the next months.

check it out! https://conferences.ncl.ac.uk/bspr-eupa2023/ 

We are super happy to have this article finally out in the Journal of Medicinal Chemistry.

https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00671

Congratulations to all involved, particularly Rachel and José who lead this work.

A warm welcome to our new visiting students from Madrid. Alba² and Marina will be working with José on ubiquitylation and cancer-related projects.