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Two new collaborative papers in Nature and Nature Communications!

Great collaborations with the van den Berg-Lab and Lowe-Lab leading to fantastic papers in Nature and Nature Communications, respectively!

Super work from Tiaan and Andy! Well done!

Abellon-Ruiz, J., Jana, K., Silale, A., Frey, A., Baslé, A., Trost, M., Kleinekathöfer, U., and van den Berg, B., BtuB TonB-dependent transporters and BtuG surface lipoproteins form stable complexes for vitamin B12 uptake in gut Bacteroides. (2023), Nature, Jun;618(7965):583-589.

Al-Jourani, O., Benedict,, Ross, J., Layton, A., van der Peet, P., Marando, V.M., Bailey, N.P., Heunis, T., Manion, J., Mensitieri, F., Franklin, A., Abellon-Ruiz, J., Oram, S.L., Parsons, L., Cartmell, A., Wright, G.S.A., Baslé, A., Trost, M., Henrissat, B., Munoz-Munoz, J., Hirt, R.P., Kiessling, L.L., Lovering, A., Williams, S.J., Lowe, E.C., Moynihan, P.J., Mining the human gut microbiome identifies mycobacterial D-arabinan degrading enzymes, (2023), Nature Comm, Apr 19;14(1):2233.

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Two exciting industrially funded PhD studentships available!

We have two industrially funded PhD studentships available within the EPSRC-funded Mosmed CDT with start date in Sept 2023.

Applicants should be interested/experienced in mass spectrometry. Usually, we would expect applicants to have a masters. 

The first project is with GSK to develop exciting “Mass spectrometry approaches to address capability gaps in drug discovery for membrane transporters”.

There will be a placement at GSK and the use of exciting novel technology.

The second project is with Boehringer Ingelheim to assess drug performance in vivo by establishing proteomics-based target engagement methods. We will also characterise new disease models.
This will include a placement at Boehringer Ingelheim in Germany.
Please apply here:
for questions please send an email to Matthias.
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PhD position in ubiquitylation and proteomics in the endo-lysosomal system.

Characterising the role of ubiquitylation in endo-lysosomal trafficking by highly sensitive ion mobility mass spectrometry

We are looking for a talented PhD student to join us in September 2023. Exciting novel technology, exciting, impactful biology. Apply online and send an email to Matthias to discuss.

https://www.findaphd.com/phds/project/characterising-the-role-of-ubiquitylation-in-endo-lysosomal-trafficking-by-highly-sensitive-ion-mobility-mass-spectrometry/?p150331