Welcome to the
Trost Lab

We are a research group at Newcastle University focussing on proteomics, innate immunity and drug discovery.

Proteomics

We develop and apply methods for mass spectrometry-based proteomics.

Innate Immunity and phagosome Biology

We study the role of ubiquitylation in phagosome biology and innate immunity.

Drug Discovery

We develop and apply mass spectrometry-based methods for drug discovery and chemical proteomics.

Trost lab to move to the University of Manchester

The Trost lab will move to the University of Manchester in January 2026 and join the Faculty of Biology, Medicine and Health. We will have a PhD position available with intake September 2026. We will keep some association with Newcastle University to finish off collaborations and remaining grants.

Recommendations for DIA mass spectrometry proteomics – pre-print out!

Great new output by the lab on DIA mass spectrometry proteomics recommendations! Fantastic work by Andy and Frances! https://www.biorxiv.org/content/10.1101/2025.09.22.677725v2

New paper out with Rice lab

Congratulations to Abby and Simran for their nice paper on chondrocytes! A proteomics investigation of primary human articular chondrocyte isolation https://www.sciencedirect.com/science/article/pii/S2665913125001001?via%3Dihub

Meet Our Team

We are an inclusive lab that is committed to ensuring a safe, friendly, and accepting environment for everybody.

Meihan Meng

PhD Student

Mengchun Li

PhD Student

Simran Raheja

PhD Student